diff --git a/src/video/vid_s3.c b/src/video/vid_s3.c
index 4a0ffc993..2b14284c7 100644
--- a/src/video/vid_s3.c
+++ b/src/video/vid_s3.c
@@ -10131,7 +10131,8 @@ static int vram_sizes[] = {
 static void
 s3_disable_handlers(s3_t *s3)
 {
-    s3_io_remove(s3);
+    if (s3->pci)
+        s3_io_remove(s3);
 
     mem_mapping_disable(&s3->linear_mapping);
     mem_mapping_disable(&s3->mmio_mapping);